298. Peripheral inflammation, Physical Activity and Cognition in Bipolar Disorder

Association of peripheral inflammation with body mass index and depressive relapse in bipolar disorder.

Bipolar I disorder (BD) is associated with increased inflammation, which is believed to be central to disease etiology and progression. However, BD patients also have high rates of obesity, itself an inflammatory condition, and the relative contributions of mood illness and obesity to inflammation are unknown. Moreover, the impact of inflammation on clinical illness course has not been well stu...

Social cognition and functional capacity in bipolar disorder and schizophrenia.

Social cognition is a functionally relevant predictor of capacity in schizophrenia (SZ), though research concerning its value for bipolar disorder (BD) is limited. The current investigation examined the relationship between two social cognitive factors and functional capacity in bipolar disorder. This study included 48 individuals with bipolar disorder (24 with psychotic features) and 30 patien...

Social Cognition and Cognitive Flexibility in Bipolar Disorder

Contextual Social Cognition Impairments in Schizophrenia and Bipolar Disorder

BACKGROUND The ability to integrate contextual information with social cues to generate social meaning is a key aspect of social cognition. It is widely accepted that patients with schizophrenia and bipolar disorders have deficits in social cognition; however, previous studies on these disorders did not use tasks that replicate everyday situations. METHODOLOGY/PRINCIPAL FINDINGS This study ev...

Endothelial and inflammation markers in schizophrenia and bipolar disorder